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Hepatitis C risk factors: how it spreads and who is at risk

Hepatitis C is a liver infection caused by a virus that spreads through contact with an infected person's blood. Here is what the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and MedlinePlus say about how it spreads, who is more likely to get it, and how to lower your risk.

Last reviewed: By the uncovermyrisk.com editorial team Educational only, not medical advice.

What hepatitis C is

Hepatitis C is a viral infection that causes inflammation and damage in the liver (NIDDK). It can be acute, a short-term infection that goes away, or chronic, a long-lasting infection where the virus stays in the body (NIDDK). NIDDK says more than half of people with acute hepatitis C go on to develop chronic hepatitis C, and MedlinePlus says this happens for most people (NIDDK) (MedlinePlus).

Researchers estimate that less than 1% of people in the United States are infected, and that chronic hepatitis C still affects more than 2 million people in the US (NIDDK). In countries where it is most common, in parts of Eastern Europe, Africa, the Middle East and Asia, an estimated 2% to 6% of people are infected (NIDDK).

How the virus spreads

The hepatitis C virus spreads through contact with an infected person's blood (NIDDK). NIDDK and MedlinePlus list these ways (NIDDK) (MedlinePlus):

In the United States, injecting drugs is the most common way people get hepatitis C (NIDDK) (MedlinePlus). Before 1992 it also commonly spread through blood transfusions and organ transplants; the US blood supply has been tested for the virus since then, and getting it this way is now very rare (MedlinePlus).

You cannot get hepatitis C from coughs or sneezes, food or water, hugging, shaking or holding hands, sitting next to someone, or sharing forks, spoons and other eating utensils (NIDDK). A baby cannot get it from breast milk, though NIDDK advises avoiding breastfeeding if the nipples are cracked or bleeding (NIDDK).

Who is more likely to get hepatitis C

Combining the NIDDK and MedlinePlus lists, hepatitis C is more common in people who (NIDDK) (MedlinePlus):

Spread through sex is possible but the chances are low (NIDDK). NIDDK names higher risk groups: men who have sex with men, and people who have multiple sex partners, have HIV or other sexually transmitted diseases, or engage in rough sex (NIDDK).

Having had hepatitis C before does not protect you: you can get it again (NIDDK).

Why chronic hepatitis C matters

Most people with hepatitis C have few or no symptoms (NIDDK) (MedlinePlus). People with chronic hepatitis C may have no symptoms until complications such as cirrhosis develop, which can be decades after infection (NIDDK). Without treatment, chronic hepatitis C can lead to cirrhosis, liver failure and liver cancer (NIDDK). See cirrhosis risk factors and liver cancer risk factors.

Because so many people have no symptoms, testing matters. NIDDK says doctors typically recommend screening at least once for all adults, during each pregnancy, for people at risk, and for anyone who asks (NIDDK). The hepatitis C screening check covers who is advised to get tested.

How to lower your risk

There is no vaccine for hepatitis C (NIDDK) (MedlinePlus). You can help protect yourself by (NIDDK) (MedlinePlus):

If you think you may have been exposed to the virus, see your doctor as soon as possible: early diagnosis and treatment can help prevent liver damage (NIDDK).

Common questions

Is hepatitis C curable?

Yes, in most cases. Antiviral medicines can cure more than 95% of people with chronic hepatitis C in 8 to 12 weeks, though some people need longer treatment (NIDDK).

How is hepatitis C different from hepatitis B?

Both viruses infect the liver and can spread through blood. Hepatitis C has no vaccine, while hepatitis B does (NIDDK). NIDDK suggests that people with hepatitis C talk with their doctor about vaccines for hepatitis A and hepatitis B, which could further damage the liver (NIDDK). See the hepatitis B risk factors guide.

Which risk factors can I change?

Past blood transfusions, being born to a mother with hepatitis C and where you were born cannot be changed. Not sharing needles or personal items like razors, choosing sterile tattoo and piercing tools, and using condoms are steps on the NIDDK and MedlinePlus lists (NIDDK) (MedlinePlus). If you have hepatitis C, NIDDK advises avoiding alcohol because it can cause more liver damage (NIDDK).

Sources

  1. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). Hepatitis C. Health information page, reviewed December 2024, accessed November 7, 2026. www.niddk.nih.gov/health-information/liver-disease/viral-hepatitis/hepatitis-c
  2. MedlinePlus (National Library of Medicine). Hepatitis C. Health topic page, last updated May 31, 2024, accessed November 7, 2026. medlineplus.gov/hepatitisc.html

Written and maintained by the uncovermyrisk.com editorial team. We do not have a medical reviewer; every claim links to its primary source above. Last reviewed: 2026-11-07. Spotted an error? See About.