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Listeria risk factors: who is most at risk from listeriosis

Listeria infection (listeriosis) is rare but can be serious for some groups. Here is what CDC and MedlinePlus say about who is most at risk, which symptoms to watch for and which foods to choose instead.

Last reviewed: By the uncovermyrisk.com editorial team Educational only, not medical advice.

CDC says to call your healthcare provider if you are pregnant and have a fever and feel more tired and achy than normal, and to say if you ate recalled food in the past two months or are worried about something you ate (CDC). Anyone who ate recalled or outbreak-linked food and has a fever and other symptoms such as fatigue and muscle aches should contact a healthcare provider (CDC).

What Listeria infection is

MedlinePlus describes listeriosis as a foodborne illness caused by Listeria monocytogenes, bacteria found in soil and water. It can be in raw foods, processed foods and foods made from unpasteurized milk, and unlike many other germs it can grow even in the cold temperature of the refrigerator (MedlinePlus).

CDC calls the infection rare but serious. It estimates that each year in the United States 1,250 people are infected and 172 people die, making Listeria infection the fourth leading cause of death from foodborne illness (CDC).

Who is most at risk

CDC says Listeria infection can be especially harmful for these groups (CDC):

Other people can be infected with Listeria, but they usually do not become seriously ill (CDC). MedlinePlus lists the same picture: anyone can get the illness, but it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems (MedlinePlus).

Pregnancy and newborns

CDC says about 1 in 25,000 pregnant women in the United States are infected with Listeria each year. The infection can spread to the baby during pregnancy and cause harm even if the mother does not feel very sick, and 1 in 4 pregnant women who get this illness lose their pregnancy or their baby shortly after birth. CDC adds that early treatment can help save the baby (CDC).

Symptoms in pregnancy are usually mild, and some pregnant women never have symptoms. Even so, CDC says infection during pregnancy usually leads to miscarriage, stillbirth, premature delivery or life-threatening infection of the newborn (CDC). See also our miscarriage risk factors and preterm birth risk factors guides.

Adults 65 and older

More than half of all Listeria infections occur among people 65 years and older. CDC explains that with age the immune system has a harder time recognizing and getting rid of harmful germs, and there is less stomach acid, which can help kill germs. Older adults with Listeria infection almost always have to be hospitalized, and 1 in 6 die (CDC).

A weakened immune system

CDC calls people with a weakened immune system the group most likely to get a Listeria infection: they make up 75% of all people with it, infection almost always leads to hospitalization, and 1 in 6 people in this group die (CDC). CDC says you likely have a weakened immune system if (CDC):

Related guides: type 2 diabetes risk factors and sepsis risk factors.

Symptoms

CDC describes two kinds of illness (CDC):

If you ate food possibly contaminated with Listeria and do not feel sick, CDC says most experts believe you do not need tests or treatment; talk with a healthcare provider if you have questions (CDC).

Safer food choices

CDC advises people in the higher-risk groups, and those who cook for them, to choose safer foods. Examples from its list (CDC):

Everyone can follow the Clean, Separate, Cook and Chill guidelines and keep up with food recalls and outbreaks (CDC). MedlinePlus adds: use precooked and ready-to-eat foods as soon as you can, heat ready-to-eat foods and leftovers until steaming hot, and wash fresh fruits and vegetables (MedlinePlus).

Salmonella is a far more common foodborne germ: CDC estimates it causes about 1.35 million infections in the United States every year (CDC). See salmonella risk factors.

E. coli is another germ spread by contaminated food. Infection with Shiga toxin-producing E. coli (STEC) can lead to hemolytic uremic syndrome (HUS), which can cause kidney failure (CDC). See our E. coli risk factors guide.

Diagnosis and treatment

CDC says Listeria infection is usually diagnosed when a laboratory test grows Listeria from a sample of body fluid or tissue. Invasive illness is treated with antibiotics; most people recover from intestinal illness without them, and people with diarrhea should drink plenty of fluids (CDC).

Common questions

I ate a recalled food. Do I need a test?

If you do not feel sick, CDC says most experts believe you do not need tests or treatment. If you have a fever and other symptoms such as fatigue and muscle aches, contact a healthcare provider and say what you ate, especially if you are pregnant, 65 or older or have a weakened immune system (CDC).

Can Listeria grow in the fridge?

Yes. MedlinePlus says Listeria can grow even in the cold temperature of the refrigerator (MedlinePlus).

Can healthy adults get seriously ill?

Other people can be infected, but CDC says they usually do not become seriously ill (CDC).

Sources

  1. Centers for Disease Control and Prevention. About Listeria Infection. August 2, 2024. www.cdc.gov/listeria/about/index.html
  2. Centers for Disease Control and Prevention. People at Increased Risk for Listeria Infection. September 24, 2025. www.cdc.gov/listeria/risk-factors/index.html
  3. Centers for Disease Control and Prevention. Symptoms of Listeria Infection. February 3, 2025. www.cdc.gov/listeria/signs-symptoms/index.html
  4. Centers for Disease Control and Prevention. Preventing Listeria Infection. January 31, 2025. www.cdc.gov/listeria/prevention/index.html
  5. MedlinePlus, National Library of Medicine. Listeria Infections. Health topic page, last updated December 1, 2025. medlineplus.gov/listeriainfections.html
  6. Centers for Disease Control and Prevention. About Salmonella Infection. October 4, 2024. www.cdc.gov/salmonella/about/index.html
  7. Centers for Disease Control and Prevention. About Escherichia coli Infection. May 14, 2024. www.cdc.gov/ecoli/about/index.html

Written and maintained by the uncovermyrisk.com editorial team. We do not have a medical reviewer; every claim links to its primary source above. Last reviewed: 2026-11-09. Spotted an error? See About.