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Stroke risk factors: blood pressure, AFib, diabetes and what you can change

High blood pressure is the main risk factor for stroke, and most strokes are linked to things you can control. Here is what the National Heart, Lung, and Blood Institute (NHLBI) and MedlinePlus list as stroke risk factors, which ones you can change, and the FAST signs that mean you should call 911.

Last reviewed: By the uncovermyrisk.com editorial team Educational only, not medical advice.

Signs of a stroke now? Call 911. Face drooping, arm weakness, slurred or strange speech: time to call 911. Every minute counts during a stroke (MedlinePlus). More in stroke warning signs.

What causes a stroke

A stroke happens when blood flow to part of the brain is blocked (ischemic stroke) or when a blood vessel in the brain bleeds (hemorrhagic stroke) (NHLBI). The NHLBI says about 87% of strokes are ischemic (NHLBI). The blockage is usually a piece of plaque or a blood clot. Plaque in the carotid arteries in the neck is a common cause (NHLBI).

A transient ischemic attack (TIA), or mini-stroke, is a blockage that breaks up before there is damage to the brain. It can turn into a full stroke (NHLBI), and having a TIA puts you at much higher risk of having a stroke (MedlinePlus).

The major risk factors

MedlinePlus lists these major risk factors (MedlinePlus):

Other factors linked to a higher risk are alcohol and illegal drug use, not enough physical activity, high cholesterol, an unhealthy diet and obesity (MedlinePlus).

More risk factors the NHLBI names

Ischemic and hemorrhagic strokes share many risk factors, such as high blood pressure, diabetes and high blood cholesterol. Blood clots can come from coronary heart disease, atrial fibrillation, heart valve disease and carotid artery disease, and bleeding can happen after taking blood thinners (NHLBI). The NHLBI also lists (NHLBI):

Which ones you can change

The NHLBI says factors you can control account for 82% to 90% of all strokes: high blood pressure, obesity, physical inactivity, poor diet and smoking (NHLBI).

Risk factorCan you change it?Where to start
High blood pressureYes, it can be treatedKnow your reading: blood pressure ranges
SmokingYesQuit smoking check
Diabetes, high cholesterolThey can be managedType 2 diabetes risk factors, high cholesterol risk factors
Obesity, inactivity, poor diet, too much alcoholYesHealthy weight, regular activity, heart-healthy eating
AFib and other heart diseaseTreatableAsk your doctor about stroke prevention; see CHA2DS2-VASc explained
Age, sex, family history, race and ethnicity, prior stroke or TIANoA reason to keep the factors you can change under control

MedlinePlus lists these heart-healthy changes to help prevent a first or a future stroke: eat a heart-healthy diet, aim for a healthy weight, manage stress, get regular physical activity, quit smoking, and manage your blood pressure and cholesterol. If these changes are not enough, you may need medicine to control your risk factors (MedlinePlus).

AFib and stroke

AFib can cause blood clots that lead to stroke (MedlinePlus). If you have been diagnosed with AFib, doctors use the CHA2DS2-VASc score to estimate stroke risk and decide about blood thinners; see CHA2DS2-VASc explained. What raises the chance of getting AFib in the first place is in AFib risk factors.

Warning signs: think FAST

Stroke symptoms often come on quickly: sudden numbness or weakness of the face, arm or leg (especially on one side), sudden confusion or trouble speaking or understanding speech, sudden trouble seeing in one or both eyes, sudden trouble walking, dizziness or loss of balance, or a sudden severe headache with no known cause (MedlinePlus). The FAST test (MedlinePlus):

The full list, including what to do while you wait, is in stroke warning signs.

Check your own risk factors

The stroke risk factor check walks through which risk factors apply to you. It does not give a percentage. For a 10-year estimate of heart attack, stroke and heart failure combined, ages 30 to 79, use the heart risk calculator (PREVENT).

Common questions

What is the biggest risk factor for stroke?

High blood pressure. MedlinePlus calls it the primary risk factor for a stroke (MedlinePlus), and it makes arteries in the brain more likely to break open (NHLBI).

Can young people have a stroke?

Yes. A stroke can happen at any age, though the risk goes up as adults get older (NHLBI).

Does a TIA raise my risk of stroke?

Yes. A TIA puts you at much higher risk of having a stroke (MedlinePlus). If a TIA is diagnosed in an emergency room, follow up as soon as possible with a primary care provider and a neurologist (NHLBI).

Sources

  1. National Heart, Lung, and Blood Institute (NIH). Stroke: Causes and Risk Factors. Last updated May 26, 2023. www.nhlbi.nih.gov/health/stroke/causes
  2. MedlinePlus (National Library of Medicine). Stroke. Last updated July 28, 2025. medlineplus.gov/stroke.html

Written and maintained by the uncovermyrisk.com editorial team. We do not have a medical reviewer; every claim links to its primary source above. Last reviewed: 2026-11-05. Spotted an error? See About.