For healthcare professionals
TIMI risk score calculator (UA/NSTEMI)
The TIMI risk score for unstable angina and non-ST elevation myocardial infarction (UA/NSTEMI) adds up seven yes or no items, one point each, for a total of 0 to 7. In the trial patients it was built from, a higher score went with more deaths, heart attacks and urgent revascularizations within 14 days. This calculator is written for clinicians and is not a diagnosis.
Findings at presentation
For a patient already diagnosed with unstable angina or NSTEMI. Answer each item. Nothing you enter leaves this page.
What you will see
The TIMI risk score from 0 to 7, the items that scored, and how often patients with the same score reached the 14-day end point in the original study.
Educational only, not medical advice. Not a diagnosis and not a treatment decision.
Source
Antman EM and colleagues, JAMA 2000: the seven items, one point each, and the 14-day event rate for each score. Item definitions as set out by Namazi and colleagues, 2022 (open access). The tests check every score and every printed rate.
Validated in
Adults with unstable angina or non-ST elevation heart attack in two international randomized trials of heparin and enoxaparin. The score was built in the 1957 patients given unfractionated heparin in the TIMI 11B trial (1996 to 1998) and checked in three more trial groups: both enoxaparin groups and the heparin group of the ESSENCE trial (1994 to 1996) (Antman 2000).
Limits
The score is for patients with a diagnosis of UA/NSTEMI, not for sorting out undifferentiated chest pain or ST elevation heart attacks. The event rates come from trial patients treated more than 25 years ago, before high-sensitivity troponin and current antiplatelet and invasive care, so they may be higher than in patients seen today. It does not replace clinical judgement, repeat ECGs or repeat troponin testing.
TIMI scoring
Each item present adds 1 point, for a total of 0 to 7 (Antman 2000).
| Item | Points if present |
|---|---|
| Age 65 or older | 1 |
| At least 3 risk factors for coronary artery disease | 1 |
| Known coronary stenosis of 50% or more | 1 |
| ST-segment deviation on the ECG at presentation | 1 |
| At least 2 anginal events in the past 24 hours | 1 |
| Aspirin use in the past 7 days | 1 |
| Elevated serum cardiac markers | 1 |
A later open-access study set out the items in more detail: the risk factors counted are diabetes, high blood pressure, high cholesterol, smoking and a family history of coronary artery disease, and ST-segment deviation means 0.05 mV or more on the ECG at admission (Namazi 2022).
Event rates by score
The end point was death from any cause, a new or recurrent heart attack, or severe recurrent ischemia needing urgent revascularization, within 14 days. These are the rates in the TIMI 11B group the score was built in (Antman 2000).
| TIMI score | Reached the 14-day end point |
|---|---|
| 0 or 1 | 4.7% |
| 2 | 8.3% |
| 3 | 13.2% |
| 4 | 19.9% |
| 5 | 26.2% |
| 6 or 7 | 40.9% |
Source: abstract of Antman and colleagues, 2000 (Antman 2000). The authors described the score as a simple way to sort patients by their risk of death and ischemic events and as a basis for treatment decisions. Current guidelines and local pathways should guide those decisions.
Related tools
The TIMI score is for patients already diagnosed with UA/NSTEMI. For adults seen in the emergency department with chest pain before a diagnosis, see the HEART score calculator. For long-term heart risk in people without symptoms, see the heart risk calculator (AHA PREVENT) or the ASCVD risk calculator (Pooled Cohort Equations). For risk before noncardiac surgery, see the Revised Cardiac Risk Index (RCRI). For suspected pulmonary embolism, see the Wells score for PE.
Sources
- Antman EM, Cohen M, Bernink PJ, et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making. JAMA. 2000;284(7):835-842. doi:10.1001/jama.284.7.835. PMID 10938172. Abstract (cohorts, the 7 predictor variables, the 14-day primary end point and the event rate by score in the TIMI 11B test cohort). pubmed.ncbi.nlm.nih.gov/10938172/
- Namazi MH, Mazloomi SS, Kalate Aghamohammadi M. Correlation Between TIMI Risk Score and the Number of Vessels Involved in the Angiographic Study; a Cross-sectional Study. Arch Acad Emerg Med. 2022;10(1):e16. doi:10.22037/aaem.v10i1.1466. PMID 35402992. Open access (CC BY 3.0). Methods 2.4 (the seven TIMI factors with their definitions, one point each). pmc.ncbi.nlm.nih.gov/articles/PMC8986490/
Written and maintained by the uncovermyrisk.com editorial team. We do not have a medical reviewer; every claim links to its primary source above. Last reviewed: 2026-11-01. Spotted an error? See About.