Screening check

Colon cancer screening: when should I start?

For most adults, screening for colorectal cancer starts at 45. A family history or some health conditions can change that. Check where you stand in under a minute.

Last reviewed: By the uncovermyrisk.com editorial team Educational only, not medical advice.

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What you will see

Whether average-risk screening applies to you at your age, or whether your history calls for a plan made with your doctor.

Educational only, not medical advice. Screening decisions are made with your doctor.

Source

US Preventive Services Task Force, 2021 recommendation. American Cancer Society colorectal cancer screening guideline.

Validated in

Adults at average risk with no symptoms. The higher-risk questions come from the American Cancer Society's definition of average risk.

Limits

Not for people with symptoms. Does not set a schedule for higher-risk people; that depends on details only your doctor can weigh.

When to start and when to stop

AgeUSPSTF 2021American Cancer Society
45 to 49Screen (grade B)Start regular screening at 45
50 to 75Screen all adults (grade A)Keep screening
76 to 85Offer selectively (grade C)Decide based on preferences, life expectancy, health and past screening
Over 85Not covered by the recommendationNo longer screen

Sources: USPSTF (USPSTF 2021), American Cancer Society (ACS).

The USPSTF lowered its start age from 50 to 45 in 2021 (USPSTF 2021). It estimates that 10.5% of new colorectal cancers occur in people younger than 50 (USPSTF 2021).

Which test, and how often?

The USPSTF does not rank the tests. Any of these counts as screening (USPSTF 2021):

TestHow oftenWhere
FIT or high-sensitivity guaiac stool testEvery yearAt home
Stool DNA-FITEvery 1 to 3 yearsAt home
CT colonographyEvery 5 yearsImaging center
Flexible sigmoidoscopyEvery 5 years, or every 10 years with a yearly FITClinic
ColonoscopyEvery 10 yearsClinic or hospital, with sedation and bowel prep

If you choose a test other than colonoscopy and the result is abnormal, it needs to be followed up with a timely colonoscopy (ACS). A home test is only a full screening plan if that follow-up happens.

When family history changes the plan

The age bands above are for people at average risk. The USPSTF recommendation does not apply to people with a previous colorectal cancer, adenomatous polyps, inflammatory bowel disease, or a known inherited syndrome such as Lynch syndrome or familial adenomatous polyposis (USPSTF 2021). The American Cancer Society also counts a family history of colorectal cancer and past radiation to the belly or pelvis as reasons someone is not at average risk (ACS).

For family history, the plan depends on who in the family had cancer and how old they were when it was found. Some people can follow the average-risk schedule; others need colonoscopy more often, possibly starting before 45 (ACS). Write down which relatives were affected and their age at diagnosis before you see your doctor.

Common questions

Why did the screening age drop to 45?

The USPSTF lowered it from 50 to 45 in 2021. It estimates that about 10.5% of new colorectal cancers occur in people under 50 (USPSTF 2021).

I am 40 and have blood in my stool. Should I wait until 45?

No. Screening ages are for people without symptoms. Bleeding, a lasting change in bowel habits or unexplained weight loss should be checked by a doctor at any age.

Do I need a colonoscopy, or is a home test enough?

Both are accepted screening options for people at average risk (USPSTF 2021). A home stool test has to be repeated on schedule, and an abnormal result needs a colonoscopy (ACS). Some higher-risk people need colonoscopy, and more often (ACS).

When can I stop?

The USPSTF recommends screening all adults through 75 and offering it selectively from 76 to 85 (USPSTF 2021). The American Cancer Society says people over 85 should no longer be screened (ACS).

Also see all screening tests by age, the lung cancer screening check, the breast cancer screening check, the cervical cancer screening check and the prostate cancer screening check.

Sources

  1. US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(19):1965-1977. www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
  2. American Cancer Society. American Cancer Society Guideline for Colorectal Cancer Screening. www.cancer.org/cancer/types/colon-rectal-cancer/detection-diagnosis-staging/acs-recommendations.html

Written and maintained by the uncovermyrisk.com editorial team. We do not have a medical reviewer; every claim links to its primary source above. Last reviewed: 2026-10-29. Spotted an error? See About.